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Vitamin D no defense against dementia

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The findings, released today in the science journal Nutritional Neuroscience reported that researchers had failed to find solid clinical evidence for vitamin D as a protective neurological agent.

“Our work counters an emerging belief held in some quarters suggesting that higher levels of vitamin D can impact positively on brain health,” says lead author Krystal Iacopetta, PhD candidate at the University of Adelaide.

Based on a systematic review of over 70 pre-clinical and clinical studies, Ms Iacopetta investigated the role of vitamin D across a wide range of neurodegenerative diseases.

“Past studies had found that patients with a neurodegenerative disease tended to have lower levels of vitamin D compared to healthy members of the population,” she says.

“This led to the hypothesis that increasing vitamin D levels, either through more UV and sun exposure or by taking vitamin D supplements, could potentially have a positive impact. A widely held community belief is that these supplements could reduce the risk of developing brain-related disorders or limit their progression.”

“The results of our in-depth review and an analysis of all the scientific literature however, indicates that this is not the case and that there is no convincing evidence supporting vitamin D as a protective agent for the brain,” she says.

Ms Iacopetta believes that the idea of vitamin D as a neuro-related protector has gained traction based on observational studies as opposed to evaluation of all the clinical evidence.

“Our analysis of methodologies, sample sizes, and effects on treatment and control groups shows that the link between vitamin D and brain disorders is likely to be associative – as opposed to a directly causal relationship,” she explains.

“We could not establish a clear role for a neuroprotective benefit from vitamin D for any of the diseases we investigated.”

Mark Hutchinson, Director of the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP) and Professor at the University of Adelaide worked with Ms Iacopetta on the research and findings.

“This outcome is important and is based on an extremely comprehensive review and analysis of current data and relevant scientific publications,” Professor Hutchinson says.

“We’ve broken a commonly held belief that vitamin D resulting from sun exposure is good for your brain.”

Interestingly, Professor Hutchinson notes that there may be evidence that UV light (sun exposure) could impact the brain beneficially, in ways other than that related to levels of vitamin D.

“There are some early studies that suggest that UV exposure could have a positive impact on some neurological disorders such as multiple sclerosis,” he says. “We have presented critical evidence that UV light may impact molecular processes in the brain in a manner that has absolutely nothing to do with vitamin D.”

“We need to complete far more research in this area to fully understand what’s happening,” says Professor Hutchinson.

“It may be that sensible and safe sun exposure is good for the brain and that there are new and exciting factors at play that we have yet to identify and measure.”

“Unfortunately however, it appears as if vitamin D, although essential for healthy living, is not going to be the miracle ‘sunshine tablet’ solution for brain-disorders that some were actively hoping for.”

Researchers involved in this systematic review are affiliated with the University of Adelaide, the University of South Australia and the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP).

Source: Eurekalert.org

Stylised image of the brain https://flic.kr/p/JYEfHr

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[podcast] Sergio Bernardini: 1st IFCC Conference “Laboratory Medicine: Meeting the Needs of Mediterranean Nations”

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Professor Sergio Bernardini, (MD, PhD), is a full professor of Clinical Biochemistry and Clinical Molecular Biology at the Department of Internal Medicine of The University of Rome Tor Vergata, and the head physician of the Clinical Molecular Biology Unit at the Tor Vergata University Hospital.

He received his degree in Medicine in 1986 and the PhD in Paediatric Sciences in 1995. He has specialized in Paediatrics (1990) and in Clinical Chemistry and Biochemistry (1998).

Professor Bernardini serves as the president of the undergraduate course in “Diagnostic laboratory techniques in the medical field” and as a clinical laboratory research consultant with Bambino Gesu’ Children’s Hospital in Rome.

He is a member of (1) the Italian Society of Clinical Biochemistry (SiBioC), (2) the SiBioC Committee of Clinical Molecular Biology, (3) the Italian Society of Biochemistry (SIB) and (4) the Italian Society of Allergology and Immunology (SIAIC). His international activities include membership of the Editorial Advisory Board of The Encyclopedia of Life Sciences.

Prof Bernardini served his first term on IFCC EB between 2012 and 2014 as IFCC Secretary.

IFCC’s Forthcoming Congresses – July Issue

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Calendario de Congresos/Conferencias y Congresos de Federaciones Regionales de la IFCC

Sep 11 – 13, 2019    COLABIOCLI Regional Congress 2019 Panama, PA
May 19 – 23, 2019 XXIII IFCC-EFLM EUROMEDLAB – BARCELONA 2019 Barcelona, ES
 Nov 17 – 20, 2019  APFCB Regional Congress 2019 Jaipur, IN
May 24 – 28, 2020   XXIV IFCC WORLDLAB – SEOUL 2020 Seoul, KR

 

 May 16 – 20, 2021 XXIV IFCC-EFLM EUROMEDLAB – MUNICH 2021 Munich, DE
 May 21 – 25, 2023   XXV IFCC-EFLM WORLDLAB-EUROMEDLAB  ROME 2023 Rome, IT

Calendario de eventos bajo auspicio de la IFCC

Jul 13 – 14, 2018 Turning Science Into Caring (TSIC) Shanghai, CN
Aug 25 – 28, 2018 15th Iranian National Congress of Biochemistry and the 6th International Congress of Biochemistry and Molecular Biology Isfahan, IR
Sep 03 – 05, 2018 AACB AIMS 2018 Combined Scientific Meeting Sydney, AU
Sep 06 – 07, 2018 6th Chromatography Mass Spectrometry Satellite Meeting and Inaugural Chromatography Mass Spectrometry Educational Workshop Sydney, AU
Sep 26 – 29, 2018 15th Annual Meeting of the German Society for Clinical Chemistry and Laboratory Medicine – The foundation for diagnosis and therapy Mannheim, DE
Sep 30 – Oct 03, 2018 Santorini Conference “Systems medicine and personalised health & therapy” – “The odyssey from hope to practice”. Santorini, GR
Oct 03 – 05, 2018 26th BCLF Meeting and 6th National Congress of MSMBLM Skopje, MK
Oct 10 – 13, 2018 5th EFLM UEMS European Congress in Laboratory Medicine Antalya, TR
Oct 16 – 17, 2018 2èmes Journées Francophones de Biologie Médicale Paris, FR
Oct 30, 2018 International Conference on Laboratory Medicine “LABORATORY MEDICINE: 25 YEARS ON” Padova, IT
Nov 01 – 04, 2018 2nd International Cell Death Research Congress Magosa, CY
Nov 09 – 12, 2018 18º Congreso Internacional del Colegio Nacional de Bacteriología Barranquilla, CO
Nov 28 – 01, 2018 II International Conference of the Bolivian Society of Clinical Biochemistry La Paz, BO
Nov 29, 2018 International Scientific Meeting of the Centre of Metrological Traceability in Laboratory Medicine (CIRME) “Standardization in Laboratory Medicine and Patient Safety” Milan, IT
Dec 07 – 08, 2018 52ème Journée de Biologie Praticienne Paris, FR
Jun 09 – 12, 2020 XXXVII Nordic Congress in Medical Biochemistry Trondheim, NO

EuroLabNews N°3 2018

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In this Issue:

  • Hot topics in Laboratory Medicine. Direct oral anticoagulants (DOACs): opportunities and challenges
  • News from EFLM Committees and Working Groups
  • EFLM events
  • Updates on EFLM Publications
  • News from EFLM National Societies
  • Changing of the Guard in EFLM National Societies
  • Calendar of EFLM events and events under EFLM auspices

Click here to access the May-June issue of EuroLabNews.

 

2nd EFLM Strategic Conference The end of laboratory medicine as we know it?

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Handling disruption of Laboratory Medicine in digital health.

Date: 18-19 June 2018, Mannheim, Germany.

The conference will consider the impact that the on-going digitalization of technologies and a digitalized society will have on the medical laboratory in future health care. We contend that such changes enable Digital Health that will be disruptive for Laboratory Medicine as we know it, because they will change our capabilities to compile, integrate and visualize complex diagnostic data as well as providing the opportunity for radical changes to diagnostic health strategies.

With the digital revolution spreading into every realm of modern medicine, we will experience a democratisation of health care, i.e. a comprehensive data usage not just being in the hands of health care professionals, but also in the patients´. Indeed, a central concept of digital health medicine is patient empowerment as demonstrated by key words like “electronic health record”, “patient access”, “health apps”, “wearable health tech” etc. In this rapidly changing health care environment, Laboratory Medicine must redefine its positions, not only acting in its classical role as provider of laboratory results, but also adopting new roles and responsibilities in the clinical dialogue.

Download SCIENTIFIC PROGRAMME

Venue Congress: Center Rosengarten Mannheim. Meeting room: Hall 3.7 Arnold Schönberg Rosengartenplatz 2, Mannheim

No more information is available on infobioquimica.org.
For further requests, you can contact the organizers of the event.

IFCC’s Forthcoming Congresses – May Issue

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Calendar of IFCC Congresses/Conferences and Regional Federation’s Congresses

Jun 20 – 22, 2018 International IFCC Course on Flow Cytometry Istanbul, TR
 Jul 02 – 04, 2018 1st  IFCC, EFLM, AFCB Conference “Laboratory Medicine: Meeting the needs of Mediterranean Nations”  Rome, IT
 Sep 11 – 13, 2019    COLABIOCLI Regional Congress 2019 Panama, PA
May 19 – 23, 2019 XXIII IFCC-EFLM EUROMEDLAB – BARCELONA 2019 Barcelona, ES
 Nov 17 – 20, 2019  APFCB Regional Congress 2019 Jaipur, IN
May 24 – 28, 2020   XXIV IFCC WORLDLAB – SEOUL 2020 Seoul, KR

 

 May 16 – 20, 2021  XXIV IFCC-EFLM EUROMEDLAB – MUNICH 2021 Munich, DE
 May 21 – 25, 2023    XXV IFCC-EFLM WORLDLAB-EUROMEDLAB  ROME 2023 Rome, IT

Calendar of events with IFCC auspices

May 23 – 25, 2018 21st Serbian Congress of Medical Biochemistry and Laboratory Medicine with international participations Belgrade, SRB
May 23 – 25, 2018 14th EFLM Symposium for Balkan Region Belgrade, SRB
May 24 – 25, 2018 XVI Meeting of the SEQCML Scientific Committee Madrid, ES
May 30 – 31, 2018 The new era of Laboratory Medicine: from Diagnosis to Clinical Management Erice, IT
Jun 03 – 06, 2018 CSCC 2018 Annual Conference Ottawa, CA
Jun 05 – 06, 2018 SERbian BIomarker Symposium (SERBIS) 2018 Men’s and Women’s Health: Biomarkers in Clinical Practice and Future Approaches Belgrade, SRB
Jun 06 – 08, 2018 Focus 2018 – Annual Meeting of ACB Manchester, UK
Jun 12 – 15, 2018 XXXVI Nordic Congress of Clinical Chemistry Helsinki, FI
Jun 18 – 19, 2018 2nd EFLM Strategic Conference “The end of Laboratory Medicine as we know it? Handling disruption of Laboratory Medicine in digital health” Mannheim, DE
Jun 21 – 22, 2018 7th International Symposium on Critical Care Testing and Blood Gases Antibes, FR
Jun 27, 2018 Student Conference prior the Clinical Chemistry Iberoamerican symposium and Expolab, Guatemala 2018 Guatemala City, GT
Jun 28 – 29, 2018 Clinical Chemistry Iberoamerican Symposium and Expolab Guatemala 2018 Guatemala City, GT
Jun 30 – July 03, 2018 International Society for Enzymology Conference Naxos, GR
Jul 13 – 14, 2018 Turning Science Into Caring (TSIC) Shanghai, CN
Aug 25 – 28, 2018 15th Iranian National Congress of Biochemistry and the 6th International Congress of Biochemistry and Molecular Biology Isfahan, IR
Sep 03 – 05, 2018 AACB AIMS 2018 Combined Scientific Meeting Sydney, AU
Sep 06 – 07, 2018 6th Chromatography Mass Spectrometry Satellite Meeting and Inaugural Chromatography Mass Spectrometry Educational Workshop Sydney, AU
Sep 26 – 29, 2018 15th Annual Meeting of the German Society for Clinical Chemistry and Laboratory Medicine – The foundation for diagnosis and therapy Mannheim, DE
Sep 30 – Oct 03, 2018 Santorini Conference “Systems medicine and personalised health & therapy” – “The odyssey from hope to practice”. Santorini, GR
Oct 03 – 05, 2018 26th BCLF Meeting and 6th National Congress of MSMBLM Skopje, MK
Oct 10 – 13, 2018 5th EFLM UEMS European Congress in Laboratory Medicine Antalya, TR
Oct 16 – 17, 2018 2èmes Journées Francophones de Biologie Médicale Paris, FR
Oct 30, 2018 International Conference on Laboratory Medicine “LABORATORY MEDICINE: 25 YEARS ON” Padova, IT
Nov 01 – 04, 2018 2nd International Cell Death Research Congress Magosa, CY
Nov 09 – 12, 2018 18º Congreso Internacional del Colegio Nacional de Bacteriología Barranquilla, CO
Nov 28 – 01, 2018 II International Conference of the Bolivian Society of Clinical Biochemistry La Paz, BO
Nov 29, 2018 International Scientific Meeting of the Centre of Metrological Traceability in Laboratory Medicine (CIRME) “Standardization in Laboratory Medicine and Patient Safety” Milan, IT
Dec 07 – 08, 2018 52ème Journée de Biologie Praticienne Paris, FR
Jun 09 – 12, 2020 XXXVII Nordic Congress in Medical Biochemistry Trondheim, NO

Endocrine Board Review

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The Endocrine Board Review (EBR) is case-based course that provides a consolidated review for endocrine fellows planning to take the 2018 endocrine board exam. It is also an ideal tool for practicing physicians preparing to re-certify, or for those seeking an intensive knowledge assessment. THE EBR program is designed as a mock exam with rapid-fire questions emulating the format and subject matter of the ABIM’s Endocrinology, Diabetes, and Metabolism Certification Examination.

The EBR Online session recordings are an interactive recording of the entire meeting, where you can re-test and compare scores with your peers, and receive customized score reports for each topic area.

Endocrine Board Review 2018 will take place September 4–5, 2018 at the Intercontinental Hotel Miami, in Miami, Florida.

endocrine.org/ebr/2018/program

More information

No more information is available on infobioquimica.org.
For further requests, you can contact the organizers of the event.

EFLM live webinar “The order of draw”

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EFLM webinar “The order of draw” by Dr. Michael Cornes starts next Tuesday, 15th May at 18:00 CET.

Speaker: Michael Cornes (UK)

Moderator: João Tiago Guimarães (PT)

Register for it and obtain presentation handouts in advance: elearning.eflm.eu

National and international (WHO, CLSI) guidelines recommended that order of draw of blood during phlebotomy should be blood culture/sterile tubes, then plain tubes/gel tubes, then tubes containing additives. This prevents contamination of sample tubes with additives from previous tubes for example sodium citrate or more commonly potassium EDTA (K3EDTA).

These recommendations are based on a case report by and a follow up study by Calam and Cooper in 1982 which reported that incorrect order of draw caused hyperkalaemia and hypocalcaemia. By measuring EDTA, it has been demonstrated that reverse order of draw of blood samples using closed loop venesection systems does not cause EDTA contamination. It is difficult to reconcile the directly conflicting results of these studies but it may be that reversed order of draw using poor technique and/or difficult venepuncture may result in sample tube cross-contamination.

It has been shown that contamination is still relatively common and may be difficult to identify. As this is not due to reversed order of draw of blood samples in a closed loop system other mechanisms must be in operation. Here I will present the evidence for and against the need to follow an order of draw.

No more information is available on infobioquimica.org.
For further requests, you can contact the organizers of the event.

[webinar] Integration and Impact of High Sensitive Troponin Testing in Improving Patient Care

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Moderator: Dr. Pradeep Dabla

Presentation Title: Performance of Highly Sensitive Troponin – Pr. Damien Gruson

Presentation Title: Clinicl application of Highly Sensitive troponin – Dr. Raphael Twerenbold

Agenda

       

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